Best Pet Friendly Hotels in Downtown Greenville SC

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Greenville a vibrant city nestled in the foothills of the Blue Ridge Mountains, offers a perfect blend of charming Southern hospitality and modern amenities. Travelers exploring this beautiful destination with their furry companions will be delighted to discover a range of pet-friendly hotels in the lively heart of downtown Greenville. These cozy accommodations not only provide a comfortable stay for you and your pet but also offer convenient access to the city's top attractions, dining, and entertainment options.

From boutique hotels with personalized service to well-known chains that cater to pet lovers, Greenville boasts a diverse selection of pet-friendly accommodations to suit every traveler's needs. Many of these hotels go above and beyond to ensure a pleasant stay for both you and your four-legged friend, with amenities such as pet beds, food bowls, and even special treats upon arrival. Imagine strolling along Main Street, with your faithful companion by your side, enjoying the bustling energy of downtown Greenville and the warm welcome extended to pets throughout the city.

As you plan your visit to Greenville, rest assured that the city is not only pet-friendly but also incredibly welcoming to travelers seeking a memorable experience. Whether you're looking to explore the picturesque Falls Park on the Reedy or indulge in the culinary delights of the local dining scene, having a pet-friendly hotel downtown allows you to immerse yourself fully in the charm and excitement of Greenville. So pack your bags, leash up your furry friend, and get ready to create unforgettable memories in this enchanting Southern city.

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Our Top 7

(Sorted by rating & number of reviews)

1. Quality Inn & Suites Greenville I-65
2. Hampton Inn - Greenville
3. Holiday Inn Express Hotel & Suites Greenville, An Ihg Hotel
4. Days Inn By Wyndham Greenville
5. Baymont By Wyndham Greenville
6. Comfort Inn Greenville I-65
7. Best Western Greenville Inn

Top Pet Friendly Hotels Downtown Greenville SC

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Greenville
Apr 22, 2026 - Apr 23, 2026

Quality Inn & Suites Greenville I-65

6.5

Good

(218 Reviews)

+ 72 photos
Nestled in the lively heart of downtown Greenville, the Quality Inn & Suites Greenville I-65 is a pet-friendly oasis for travelers seeking comfort and convenience. This hotel welcomes pets of all sizes and offers designated pet-friendly rooms equipped with pet amenities. With its central location and friendly staff, guests can explore downtown Greenville with ease and return to a cozy room that feels like a home away from home.
Address: 941 Fort Dale Road
Rating: Good 6.5 (218 Reviews)
Rooms: 86
Price: From 82$

Hampton Inn - Greenville

8.5

Good

(64 Reviews)

+ 86 photos
As a well-known chain committed to providing a high standard of hospitality, the Hampton Inn in Greenville ensures that traveling with pets is a stress-free experience. This pet-friendly hotel offers comfortable rooms with designated pet-friendly floors, allowing guests to enjoy a peaceful stay with their furry friends by their side. Located in downtown Greenville, the Hampton Inn provides easy access to the city's main attractions, making it a popular choice for pet owners seeking convenience and comfort.
Address: 219 Interstate Drive
Rating: Good 8.5 (64 Reviews)
Rooms: 69
Price: From 116$

Exceptional Pet Friendly Hotels Downtown Greenville SC

Continuing our exploration of pet-friendly hotels in downtown Greenville this section presents a curated selection of exceptional accommodations that prioritize the comfort and well-being of both guests and their beloved pets. These hotels have been handpicked for their outstanding amenities, convenient locations, and dedicated pet-friendly services, ensuring a memorable stay for travelers exploring Greenville with their furry companions.

Holiday Inn Express Hotel & Suites Greenville, An Ihg Hotel

9.2

Good

(192 Reviews)

+ 82 photos
For travelers seeking a pet-friendly stay with a touch of luxury, the Holiday Inn Express Hotel & Suites Greenville delivers on comfort, style, and convenience. This IHG hotel welcomes pets and offers pet-friendly rooms equipped with all the necessary amenities for a comfortable stay. With its prime location in downtown Greenville and upscale facilities, the Holiday Inn Express Hotel & Suites provides a premium experience for both you and your furry friend.
Address: 100 Paul Stabler Drive
Rating: Good 9.2 (192 Reviews)
Rooms: 67
Price: From 145$

Days Inn By Wyndham Greenville

6.6

Good

(78 Reviews)

+ 34 photos
Conveniently located in downtown Greenville, the Days Inn By Wyndham Greenville offers pet-friendly accommodations that cater to travelers seeking affordability and comfort. Pet owners can enjoy spacious rooms equipped with pet amenities, allowing them to relax and unwind after a day of exploring the city's attractions. With its close proximity to downtown Greenville's vibrant dining and entertainment scene, this hotel provides a convenient base for pet owners looking to make the most of their stay.
Address: 946 Fort Dale Rd
Rating: Good 6.6 (78 Reviews)
Rooms: 39
Price: From 77$

Cozy Pet Friendly Escapes in Downtown Greenville SC

Embark on a journey of discovery with these cozy pet-friendly escapes in downtown Greenville where comfort and pet-friendly amenities meet to create a memorable experience for travelers and their furry companions. These hotels offer a tranquil and inviting atmosphere, allowing guests to unwind in a welcoming environment while exploring the charm and beauty of downtown Greenville with their pets by their side.

Baymont By Wyndham Greenville

6.4

Good

(56 Reviews)

+ 40 photos
Nestled in downtown Greenville, the Baymont By Wyndham welcomes guests and their pets with open arms, providing a pet-friendly retreat in the very heart of the city. Travelers can enjoy comfortable rooms equipped with pet amenities, ensuring a relaxing stay for both themselves and their furry friends. With its convenient location and warm hospitality, the Baymont By Wyndham is a haven for pet owners looking to experience downtown Greenville with their pets.
Address: 71 Jameson Ln
Rating: Good 6.4 (56 Reviews)
Rooms: 41
Price: From 65$

Comfort Inn Greenville I-65

8.3

Good

(253 Reviews)

+ 110 photos
Offering a blend of comfort and convenience, the Comfort Inn Greenville I-65 is a pet-friendly hotel that caters to both two-legged and four-legged guests. Pet owners will appreciate the hotel's pet-friendly policies, including designated pet areas and amenities to ensure a pleasant stay for their furry companions. Located in downtown Greenville, this hotel provides easy access to the city's attractions and dining options, making it an ideal choice for travelers exploring the area with their pets.
Address: 1029 Fort Dale Rd
Rating: Good 8.3 (253 Reviews)
Rooms: 54
Price: From 97$

Best Western Greenville Inn

7.8

Good

(285 Reviews)

+ 50 photos
Situated just a short distance from downtown Greenville, the Best Western Greenville Inn is a pet-friendly retreat for travelers looking to explore the city and its surrounding attractions. The hotel's pet-friendly rooms ensure that both you and your furry friend have a relaxing stay, complete with essential amenities and a warm, inviting atmosphere. With its convenient location and excellent customer service, the Best Western Greenville Inn is a top choice for pet owners visiting the area.
Address: 56 Cahaba Road
Rating: Good 7.8 (285 Reviews)
Rooms: 45
Price: From 135$